{
  "node_id": "fda-adaptive-clinical-trial-design-guidance-2019",
  "title": "Adaptive Designs for Clinical Trials of Drugs and Biologics Guidance for Industry",
  "domain": "Pharmaceuticals & Life Sciences",
  "version": "1.0.1",
  "last_updated": "2026-04-30",
  "bluf": "This guidance provides recommendations for the use of adaptive designs in clinical trials, as outlined in Section III…",
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  "dependencies": [
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    "iso-37301-compliance-2021"
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  "primary_citations_count": 9,
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  "citation_preview": [
    "Section I: Introduction",
    "Section III: Pre-Specified Adaptations"
  ]
}