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ICH Q1A(R2) Stability Testing of New Drug Substances and Drug Products

This guideline defines the core stability data package required for a new drug substance or drug product registration application within the ICH regions,…

What ICH Q1A(R2) Stability Testing of New Drug Substances and Drug Products requires

This guideline defines the core stability data package required for a new drug substance or drug product registration application within the ICH regions, specifying storage conditions, study durations, and data evaluation to establish a re-test period or shelf life. It applies to pharmaceutical manufacturers submitting New Drug Applications (NDAs) or Marketing Authorisation Applications (MAAs), as detailed in Section 2.1 General Principles.

Pillar: Medical & Healthcare · Authority: International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) · Version: 1.0.0 · Last updated:

Primary source: https://database.ich.org/sites/default/files/Q1A%28R2%29%20Guideline.pdf

SHA-256 integrity: ccb54beddc56c8b267968c4c9a3606a7de4b1bd6d817c660733ef8edd5cd4fd5

Primary Citations — 6 traced to source

  • ICH Q1A(R2), Section 2.1.2: Stress Testing
  • ICH Q1A(R2), Section 2.1.3: Selection of Batches

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